Ajax vs Inter Milan prediction
On Wednesday, September 17, 2025, at 22:00 GMT+3, Ajax Amsterdam will welcome Inter Milan to the Johan Cruijff ArenA for an exhilarating clash in the group stage of the Champions League. Both teams come into this fixture with contrasting form, setting the stage for what promises to be a captivating encounter. Ajax’s recent domestic success contrasts sharply with Inter’s struggles, particularly in their last outing, and this could prove pivotal in determining the outcome of the match.
Our editors have worked hard to put together a well-researched Champion League betting tips for this week and beyond.
Main Tip: Inter Milan & Over 1.5 Goals
Given the dynamics of both teams’ current forms and their recent encounters, our primary betting tip is an away win for Inter Milan (Tip 2). Although Ajax has been performing admirably at home, their record against Inter in recent meetings, notably their last direct encounter, gives the Italian side a psychological edge. With odds of 1.89 at Betwinner, this bet holds significant value, especially considering Inter’s historical prowess in the competition.
Betting Tip 2: Under 2.5 Goals
For our second betting tip, we suggest a 0:2 scoreline in favour of the visiting side. Although Inter have struggled in recent times, they have more quality than the hosts. This prediction is further bolstered by Inter’s form in the Champions League.
Betting Tip 3: Under 2.5 Goals
Our third betting tip revolves around the potential for a low-scoring match. With both teams having had mixed results recently and defensive setups likely taking precedence in this crucial tie, we advocate for betting on Under 2.5 goals. The odds for this market is stated at 2.12 on Betwinner, suggesting a copy of the tighter matches we’ve seen from both teams lately.

Statistics for Ajax Amsterdam vs Inter Milan
Ajax Amsterdam Team News!
Ajax Amsterdam enters this fixture with confidence, having recently secured a solid 3:1 home victory over PEC Zwolle. Under the guidance of manager John Gijsbert Alan Heitinga, Ajax appears to be in fine form, accumulating three wins and two draws in their last five matches across all competitions. However, their Champions League track record has been less than satisfactory, with one win and four losses in their last five appearances in the tournament. Despite their prior struggles in Europe, Ajax’s domestic performances should not be underestimated, and Heitinga’s tactical approach may pose difficulties for Inter.
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Inter Milan Team News!
On the other hand, Inter Milan comes into this match following a disappointing 3:4 loss to Juventus, marking a rather tumultuous period for them. Under the stewardship of Cristian Eugen Chivu, Inter’s recent performance has yielded two wins, one draw, and two losses across all competitions. Although their Champions League campaign last season also yielded mixed results, their historical performance in the tournament positions them as formidable opponents. Chivu’s approach will need to focus on tightening the defensive structure and ensuring that the attacking players, eager to bounce back, can capitalize on their opportunities.
H2H Statistics
The head-to-head record over the last three meetings shows a clear advantage for Inter Milan, with Ajax failing to secure a win in their previous encounters. The clashes include two victories for Inter and one draw, including the most recent meeting, which resulted in a slender 1:0 victory for the Italian side. This historical context gives Inter Milan an edge in confidence as they head into this crucial matchup.
Last Results Ajax Amsterdam
Ajax has demonstrated resilience, securing three wins and two draws in their last five matches across all competitions. Their domestic prowess has certainly bolstered their confidence, although consistency in the Champions League remains a point of concern. Their tendency to score and maintain composure, particularly at home, is a factor that could influence the outcome against Inter Milan.
Last Results Inter Milan
Inter Milan, conversely, has experienced a turbulent run of form recently, with two wins, one draw, and two defeats in their last five matches. This inconsistency may affect team morale and cohesion heading into a critical Champions League clash, propelling them to aim for an assertive response against Ajax.
Conclusion
Overall, while Ajax Amsterdam’s recent domestic form instills a sense of optimism, Inter Milan’s historical proficiency in the Champions League and their psychological advantage from past encounters position them as the favorites for this match. The blend of Ajax’s attacking flair and Inter’s defensive acumen suggests a tightly contested match, potentially yielding a scoreline that favors the Italian side. As such, an away win for Inter Milan and at least two total goals recorded, alongside betting options for a 0-2 scoreline and the possibility of under 2.5 goals, represents a strategic approach to this exciting fixture.
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